Accutane acne treatment

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Accutane acne treatment

Accutane is prescribed for patients suffering from a difficult to treat acne type. It brings good results, but it has also potentially severe side effects. This is why precautions must be taken. To know exactly what is Accutane, its benefits and also the risks you may take, here are the best articles from the net about it. Read them carefully !


Treatment of Acne With Isotretinoin – Accutane

accutane acne treatmentIsotretinoin (Accutane) is a medicine that revolutionized the treatment of acne. Accutane belongs to the family of medicines called retinoids, which are similar to vitamin A. Accutane, like other retinoids, works by altering DNA transcription. This affect decreases the size and output of sebaceous glands. It also makes the cells that are sloughed off into the sebaceous glands less sticky, and therefore less able to form blackheads and whiteheads (comedones). It also reduces the number of bacteria in the sebaceous gland and on the skin surface.

Who Takes Accutane?

Accutane is generally used for nodular, pustular acne that has not responded to full courses of several oral antibiotics. The trend in Accutane prescribing for acne has been towards using it earlier in the course of the disease, especially if there is significant scarring. While Accutane is used primarily for severe acne, it has also been used for other disorders such as psoriasis, lupus, and lichen planus, with varying degrees of success.

Starting Therapy With Accutane

Several dosing regimens are used, but the most common regimen involves starting with a low dose, then increasing the dose after several weeks. The length of the treatment course varies but generally lasts from 16 to 20 weeks. Some people notice that their acne gets worse after starting Accutane therapy. The number of acne lesions usually does not increase; rather the lesions may become redder or more painful. This is normal, lasts only a short while, and is not a reason to stop using Accutane.

Birth Defects With Accutane

The side effects of Accutane have been a controversial topic. The most noticeable, serious, side effect is its teratogenicity. This means that Accutane causes birth defects if women take it while they are pregnant. The birth defects Accutane causes include central nervous system, facial, cardiac, and thymus gland abnormalities. After Accutane treatment has been completed for one month, a woman can get pregnant without worry about birth defects. Accutane does not affect fertility, or make it difficult to get pregnant. Women who are taking Accutane should use two forms of birth control starting a month before treatment and continuing one month after treatment.

Serious Side Effects With Accutane

side effects accutaneAccutane therapy also has the following serious side effects.

*Headaches, if persistent and associated with nausea, vomiting, and blurred vision, may be a sign of a condition called pseudotumor cerebri.
*The incidence of depression, psychosis, and suicide attempts is increased, and returns to normal after discontinuing the drug.
*The production of tears in the eyes is decreased, which can cause, red eyes, itchy eyes, and possibly ulcerations of the cornea, especially with contact lens wearers.
*The ability to distinguish between shades of black and white can be decreased causing night blindness.
*Liver enzymes can be elevated causing jaundice, hepatitis, and abdominal pain.

Other Side Effects With Accutane

Accutane therapy can also cause the following less serious, but potentially annoying side effects.

*Dry skin requiring the frequent use of moisturizers
*Dry and cracking lips
*Nosebleeds
*Itchy skin (pruritis)
*Thinning hair
*Excessive peeling, especially of the palms and soles
*Muscle aches and pains, even worse with physical activity
*Increased sensitivity to the sun causing sunburns more easily
*Elevated triglyceride levels

Lab Monitoring of Accutane

Prior to starting Accutane therapy, patients should have blood work to check triglyceride levels, liver functions, and a complete blood count. Women should also have a pregnancy test. Periodically during the course of therapy, but especially one month after starting therapy, these labs are checked again.

Finishing Therapy With Accutane

A standard course of therapy is 16 to 20 weeks. At the end of 16 weeks, about 85% of patients are clear. The beneficial effects of Accutane do not stop when the drug is discontinued. A further reduction of acne lesions and improvement of scarring is seen for months after treatment has stopped. Another beneficial affect of Accutane is that after a course of the drug, the skin usually responds better to conventional acne therapy.

Final Thoughts About Accutane

The side effects of Accutane therapy have prevented some people from considering it as a viable therapy. However, the majority of side effects go away after the drug is discontinued with the notable exception of the birth defects. Despite its side effects, Accutane remains the most powerful and promising therapy for moderate to severe acne. Used in a prudent manner, with careful monitoring, it can change the life of an adolescent or young adult.

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Treatments For Acne: Accutane

accutane acne treatmentIf all other acne treatments fail, you may be forced to consider the possibility of using Accutane (also known as Roaccutane in some countries), which many people have come to regard as the acne « wonder drug ».

What is Accutane?

Accutane, is a Vitamin A derivative, and is used exclusively in the treatment of severe inflammatory or nodular-cystic acne.

How Does Accutane Work?

Accutane acts by reducing the amount of oil produced by the skin’s sebaceous glands. It may take a while to begin producing results (an average 6-8 weeks), and acne typically worsens during the initial period of treatment.

The medication is usually started in small doses which are increased incrementally until the acne responds. The dosage is then cycled as necessary for 4-5 months, the aim being to reduce the body’s dependency on the drug.

The Benefits of Accutane

Accutane shouldn’t be regarded as a permanent cure for acne, although if you suffer from teenage acne, it will often buy you sufficient time while you « grow out of it ». Most users will be acne-free for months, even years, after finishing taking Accutane, but 10% of users are unlucky enough to find their acne re-occuring in less than 12 months after the end of a course.

The Drawbacks of Accutane

While Accutane represents an enormous breakthrough on the route towards an effective treatment for acne, the decision to start taking it isn’t one to be considered lightly.

The reason for this is that as medications go, it’s pretty toxic – hard on the liver and the body’s ability to process cholesterol. In addition, it has been shown to cause severe birth defects, including mental and physical retardation. This means that pregnancy is definitely not an option for women using Accutane. The recommendation is that women use a barrier protection method in addition to any hormone-based birth control methods such as pills and implants, as Accutane has been known to interfere with their effectiveness.

Other side effects include the following:

Chapped lips 90%
Reduced night vision Depression and/or suicidal thoughts Dry and itchy skin 80%
Dryness of nose, mild nosebleed 80%
Headache 5%
Sensitivity to sunburn 5%
Intestinal disruption 5%
Irritation of the eyelids and eyes 40%
Joint and muscle pains 15%
Rash 7%
Hair thinning 10%
Urinary symptoms 5%

Getting Access To Accutane

what is accutaneIn the majority of countries, you can only Accutane is by via a dermatologist prescription. Dermatologists and pharmacists in the U.S are also required by the FDA’s iPledge program to put potential users through an assessment system to determine their suitability for the drug.

While it can be difficult, frustrating and expensive to obtain Accutane from a dermatologist, we strongly advise against buying Accutane without medical supervision. As I’ve explained above, this drug is highly toxic, and because of this requires customised usage, with your liver and cholesterol levels being regularly monitored via blood tests. It’s easy to dismiss these safeguards if you simply order your meds online, if you’re unlucky, this stuff can cause you more serious problems than cystic acne, so please, think carefully!

I know that it’s inevitable that a proportion of those reading this will choose to ignore my advice, so if you feel you must buy your Accutane off prescription, at least do it via a reliablee source which provides the information you need to take the drug with a basic degree of safety.

Reputable online stores which will supply Accutane without prior prescription (some have you fill in an online form in order to assess your suitability) include:

Accutane from Aclepsa.com
Accutane from ePharmacies.com

If you determined to use Accutane without a prescription, you should make sure you follow the basic guidelines for taking the drug and looking after your health while you’re on it. I’ve outlined them below.

Directions for taking Accutane

Take Accutane twice each day with a meal with a full glass of water, milk, or juice. . Swallow the capsule, don’t suck or chew it.

Start with the lowest dose of Accutane (10mg). Stay at this dose for 6-8 before considering increasing the dose.

You should seek out take regular blood (liver function and blood lipids) tests while you are taking Accutane. Don’t be afraid seek out a physician to give you the test – you won’t get into trouble. A baseline blood chemistry test should be taken before you start your course. In order to be accurate, these tests should be done when you have fasted for 12 hours.

Regardless of the condition of your acne, you should not continue to take Accutane beyond 20 weeks, as your body cannot tolerate long periods of being subjected to such a toxic drug. If you find the acne returning, go see your doctor rather than just resuming the Accutane.

At the end of a course of Accutane, you should give yourself at least a 2-month « rest period » during which you observe any further changes to your skin. This is because your acne may continue to get better even though you are no longer taking Accutane. If you are still growing, you may need a longer « rest period. »

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Accutane acne treatment

side effects of accutaneGeneric Name: isotretinoin (oral)
Brand Names: Accutane, Amnesteem, Claravis, Sotret

What is Accutane?

Accutane is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Accutane is used to treat severe nodular acne. It is usually given after other acne medicines or antibiotics have been tried without successful treatment of symptoms.

Accutane may also be used for other purposes not listed in this medication guide.

Important information about Accutane

Accutane can cause severe, life-threatening birth defects. Never use Accutane if you are pregnant.

Women of child-bearing potential must agree in writing to use two specific forms of birth control and have regular pregnancy tests before, during, and after taking isotretinoin.

Accutane is available only under a special program called iPLEDGE. It is dangerous to try and purchase Accutane on the Internet or from vendors outside of the United States.

Do not take vitamin supplements containing vitamin A while you are taking isotretinoin. Do not donate blood while taking Accutane and for at least 30 days after you stop taking it.

What should I discuss with my healthcare provider before taking Accutane?

Accutane is available only under a special program called iPLEDGE. You must be registered in the program and sign documents stating that you understand the dangers of this medication and that you agree to use birth control as required by the program. Ask your doctor or call the drug maker if you have questions about the program or the written requirements.

It is dangerous to try and purchase Accutane on the Internet or from vendors outside of the United States. The sale and distribution of Accutane outside of the iPLEDGE program violates the regulations of the U.S. Food and Drug Administration for the safe use of this medication.

Do not use this medication if you are allergic to isotretinoin or to parabens, or if you are pregnant or may become pregnant.

To make sure you can safely take Accutane, tell your doctor if you have any of these other conditions:

*a personal or family history of depression or mental illness;
*heart disease, high cholesterol or triglycerides;
*osteoporosis or other bone disorders;
*an intestinal disorder such as inflammatory bowel disease, ulcerative colitis, or Crohn’s disease;
*diabetes;
*asthma;
*an eating disorder (anorexia nervosa); or
*liver disease.

Accutane can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Even one dose of Accutane can cause major birth defects of the baby’s ears, eyes, face, skull, heart, and brain. Never use Accutane if you are pregnant.

For Women: Unless you have had your uterus and ovaries removed (total hysterectomy with oophorectomy) or have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential.

Even women who have had their tubes tied are required to use birth control while taking Accutane.

You must have a negative pregnancy test 30 days before you start taking Accutane. A pregnancy test is also required before each prescription is refilled, right after you take your last dose of Accutane, and again 30 days later. All pregnancy testing is required by the iPLEDGE program.

You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking Accutane and ending 30 days after you stop taking it. Both a primary and a secondary form of birth control must be used together.

Primary forms of birth control include:

*tubal ligation (tubes tied);
*vasectomy of the male sexual partner;
*an IUD (intrauterine device);
*estrogen-containing birth control pills (not mini-pills); and
*hormonal birth control patches, implants, injections, or vaginal ring.

Secondary forms of birth control include:

*a male latex condom plus spermicidal foam or gel;
*a diaphragm plus spermicidal foam or gel;
*a cervical cap plus spermicidal foam or gel; and
*a vaginal sponge containing spermicide.

Stop using Accutane and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant. If you get pregnant while taking Accutane, call the iPLEDGE pregnancy registry at 1-866-495-0654.

It is not known whether isotretinoin passes into breast milk. Do not take Accutane without first talking to your doctor if you are breast-feeding a baby.

How should I take Accutane?

accutane for acneTake Accutane exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Each prescription of Accutane must be filled within 7 days of the date it was prescribed by your doctor. You will receive no more than a 30-day supply of Accutane at one time.

Always take Accutane with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible. Take Accutane with food or milk. Take this medication for the entire length of time prescribed by your doctor. Your acne may seem to get worse at first, but should then begin to improve.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

Never share this medicine with another person, even if they have the same symptoms you have. Store Accutane at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include headache, dizziness, vomiting, stomach pain, warmth or tingling under the skin, swelling of the lips, and loss of balance or coordination.

What should I avoid while taking Accutane?

Do not take vitamin supplements containing vitamin A while you are taking Accutane.

Do not donate blood while taking Accutane and for at least 30 days after you stop taking it. Donated blood that is later given to pregnant woman could lead to birth defects in her baby if the blood contains any level of Accutane.

Do not use wax hair removers or have dermabrasion or laser skin treatments while you are taking Accutane and for at least 6 months after you stop taking it. Scarring may result.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Accutane can make your skin more sensitive to sunlight and sunburn may result. Accutane may impair your vision, especially at night. Be careful if you drive or do anything that requires you to see clearly.

Accutane side effects

acne accutaneGet emergency medical help if you have any of these signs of an allergic reaction to Accutane: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Accutane and call your doctor at once if you have any of these serious side effects:

*depressed mood, trouble concentrating, sleep problems, crying spells, aggression or agitation, changes in behavior, hallucinations, thoughts of suicide or hurting yourself;

*sudden numbness or weakness, especially on one side of the body;

*blurred vision, sudden and severe headache or pain behind your eyes, sometimes with vomiting;

*hearing problems, hearing loss, or ringing in your ears;

*seizure (convulsions);

*severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;

*loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

*severe diarrhea, rectal bleeding, black, bloody, or tarry stools;

*fever, chills, body aches, flu symptoms, purple spots under your skin, easy bruising or bleeding;

*severe blistering, peeling, and red skin rash; or

*joint stiffness, bone pain or fracture.

Less serious Accutane side effects may include:

*joint pain, back pain;

*feeling dizzy, drowsy, or nervous;

*dryness of the lips, mouth, nose, or skin; or

*cracking or peeling skin, itching, rash, changes in your fingernails or toenails.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Accutane?

Before taking Accutane, tell your doctor if you are also taking:

steroids (prednisone and others);

seizure medication such as phenytoin (Dilantin); or

a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Doryx, Vibramycin), minocycline (Minocin), or tetracycline (Brodspec, Sumycin, Tetracap).

This list is not complete and other drugs may interact with Accutane. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

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As you see, the Accutane acne treatment is something that has to be taken seriously, and I hope all these informations will help you to do so.

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