Adapalene acne treatment

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Adapalene acne treatment

Adapalene is a topical medication for acne treatment. It may be used in conjunction with other products and can causes some side effects. If you’re looking to use it, here are the best articles from the net about Adapalene to give you as much informations as needed.


What is adapalene topical (Differin)?

adapalene for acneAdapalene is a topical (applied to the skin) medication similar to vitamin A. It helps the skin renew itself.

Adapalene topical is used to treat severe acne in people who are at least 12 years old.

Adapalene topical may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of adapalene topical (Differin)?

Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

During your first 4 weeks of using adapalene topical, your skin may be dry, red, or scaly. You may also feel some burning or stinging. Call your doctor if these side effects are severe.

Less serious side effects are more likely to occur, such as mild burning, warmth, stinging, tingling, itching, redness, or irritation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about adapalene topical (Differin)?

Avoid getting this medication in your eyes, in the creases of your nose, or on your lips. If it does get into any of these areas, wash with water. Do not use adapalene topical on sunburned, windburned, dry, chapped, irritated, or broken skin. Also avoid using this medication in wounds or on areas of eczema. Wait until these conditions have healed before using adapalene topical.

Do not use skin products that contain alpha hydroxy or glycolic acid while you are also using adapalene topical.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medication skin products unless your doctor has told you to.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Adapalene topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

What should I discuss with my healthcare provider before using adapalene topical (Differin)?

adapalene for acneYou should not use this medication if you are allergic to adapalene.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether adapalene topical passes into breast milk or if it could harm a nursing baby. Do not use adapalene topical without telling your doctor if you are breast-feeding a baby.

How should I use adapalene topical (Differin)?

Use adapalene topical exactly as your doctor has prescribed it for you. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects. Do not use this medication for longer than your doctor has prescribed.

Adapalene topical is usually applied once daily in the evening.

Wash your hands before applying adapalene topical.

Clean your skin with a mild cleanser (not soap) before applying the medication. Pat the skin dry with a clean towel.

Apply the medication in a thin layer to the entire face or other affected skin areas. Do not apply any other skin products unless your doctor has told you to.

Use this medication for as many days as it has been prescribed for you even if you think it is not working. It may take weeks or months of use before you notice improvement in your skin. Your acne may get slightly worse for a short time when you first start using the medication. Call your doctor if skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks.

Store adapalene topical at room temperature away from moisture and heat.

What happens if I miss a dose (Differin)?

Apply the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not apply extra medicine to make up the missed dose.

What happens if I overdose (Differin)?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.

What should I avoid while using adapalene topical (Differin)?

adapalene for acneAvoid getting this medication in your eyes, in the creases of your nose, or on your lips. If it does get into any of these areas, wash with water. Do not use adapalene topical on sunburned, windburned, dry, chapped, irritated, or broken skin. Also avoid using this medication in wounds or on areas of eczema. Wait until these conditions have healed before using adapalene topical.

Do not use skin products that contain alpha hydroxy or glycolic acid while you are also using adapalene topical.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medication skin products unless your doctor has told you to.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Adapalene topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

What other drugs will affect adapalene topical (Differin)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied adapalene. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about adapalene topical.

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Adapalene in the Treatment of Acne

Adapalene is a very effective topical retinoid used to treat acne. It is usually well tolerated than other retinoids like tretinoin and tazarotene.

The mode of action of adapalene in acne is similar to other retinoids. It normalizes the thickening and differentiation of the cells lining the hair follicle. Adapalene also inhibits the production of sebum and has anti-inflammatory effects on the acne bumps.

In Which Types of Acne is Adapalene Effective?

Adapalene is the medication of choice along with other retinoids in mild comedonal acne and effective as a combination therapy in moderate popular and severe pustular acne.

Mode of Application of Adapalene in Acne Treatment

adapalene for acneAdapalene is claimed to be less irritating than other topical retinoids. Adapalene causes superficial peeling of the skin, in addition to its anti-acne actions.

Before bed time, wash and dry the face.
Adapalene is applied to the acne bumps in a thin layer. In the first week, apply the medication only to the bumps, and not to the entire skin so as to limit any potential irritant reaction.
Avoid areas near the eyes, eyelids, nostrils and around the lips.
Adapalene should be applied to the acne-affected areas once a day before retiring to bed at night, after washing and drying the area. A thin film of the gel should be applied, taking care to avoid eyes and lips.

What are the Adverse Effects of Adapalene?

10-50% of patients on adapalene in various studies have experienced dryness and redness accompanied by a burning sensation or itching following initial applications. These side effects can be countered by application of adapalene only to the acne lesions in the first one to two weeks of treatment.

As with other topical retinoids, adapalene can cause sun sensitization and contact irritant and allergic reactions. Hence adapalene should only be used at night and a protective, non-comedogenic sun screen should be worn during daytime.
A flare up of acne bumps may be experienced by some users after two to three weeks of adapalene treatment. This should not be confused with allergic reaction. It is only an inflammatory blow up of hidden comedones and papular acne and is a good sign that treatment is finally attacking the acne at its roots. There is no need to stop adapalene during these flare ups, amount and frequency of application may be reduced.
Adapalene is best avoided in pregnancy and breast feeding.

Adapalene Combination Therapies in Acne Treatment

A good number of studies have shown the benefit of combining adapalene with topical antibiotics, benzoyl peroxide and/or systemic antibiotics.

The advantages of these combinations are many:

Combination of adapalene and topical antibiotics like clindamycin results in a more rapid and significantly greater clearance of moderate pustular types of acne.
Application of adapalene 0.1% gel at night and benzoyl peroxide 2.5% to 5% gel in the morning cleared acne faster than both agents used alone. This combination can cause irritant reaction in sensitive individuals; hence, to start with, lower concentrations and limited area and frequency of applications are advised.
In severe types of acne, adapalene gives better results with oral antibiotics like tetracycline, minocycline, doxycycline, erythromycin or azithromycin.
Combining adapalene to antibiotics also reduces the chances of antibiotic resistance to Propionibacterium acnes and other bacteria.

Adapalene is thus a very useful and effective topical retinoid in the mild to severe types of acne, used alone or in combination with other systemic or topical acne medications.

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Hope these articles helped you to decide whether Adapalene is appropriate for your acne treatment or not.

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