Minocycline acne treatment


Minocycline acne treatment

Minocycline is an oral antibiotic used to treat from moderate to severe forms of acne. But it appears through years that the side effects of this acne treatment are important and are causing controversy. So, to make your own opinion, here are the best articles from the net about minocycline. You’ll see if this antibiotic is made for you and if you accept the risks of side effects.

MINOCYCLINE – Oral, Brand name(s): Dynacin, Minocin USES:

minocycline acneMinocycline is used to treat a wide variety of infections, including acne. This medication belongs to the class of antibiotics known as tetracyclines. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu).Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.This drug may also be used to treat rheumatoid arthritis.


Read the Patient Information Leaflet (available with some brands of this medication) provided by your pharmacist before you start using minocycline and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Swallow this medication whole.Take each dose with a full glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not lie down for 10 minutes after taking this medication. For this reason, do not take it right before bedtime.

You may take minocycline with food or milk if stomach upset occurs, unless your doctor directs you otherwise.Take this medication 2-3 hours before or after taking any medications containing magnesium, aluminum, or calcium. Some examples include antacids, quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), vitamins/minerals, and sucralfate.

Follow the same instructions if you also take bismuth subsalicylate, iron, and zinc. They bind with minocycline preventing its full absorption. Dosage is based on your medical condition and response to therapy. If you have kidney disease, you should not take more than 200 milligrams per day.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens.


Nausea, vomiting, diarrhea, lightheadedness, dizziness, unsteadiness, drowsiness, mouth sores, or cough may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: sunburn (sun sensitivity), muscle pain, difficult or painful swallowing, change in the amount of urine, pink urine, brown/gray tooth discoloration, blue/gray/brown discoloration of the skin/lips/tongue/gums, numbness/tingling of the hands/feet, unusual fatigue, stopping of menstrual periods, new signs of infection (e.g., fever, chills, persistent sore throat).

Tell your doctor immediately if any of these rare but very serious side effects occur: hearing changes (e.g., ringing in the ears, decreased hearing), easy bruising/bleeding, headache, vision changes (e.g., blurred vision).This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur while receiving therapy or even weeks to months after treatment has stopped.

Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, skin lesions/sores, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, loss of appetite/weight loss, new or worsening swelling/pain in the joints, swollen glands, chest pain, fast/irregular heartbeat, severe stomach/abdominal pain, yellowing eyes/skin, dark urine.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


minocycline side effectsBefore taking minocycline, tell your doctor or pharmacist if you are allergic to it; or to other tetracyclines (e.g., doxycycline); or if you have any other allergies.

This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, problems swallowing, esophagus problems (e.g., hiatal hernia, reflux disease-GERD).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

Limit alcoholic beverages.To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.

Before having surgery, tell your doctor or dentist that you are using minocycline.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects.

This medication should not be used in children younger than 8 years of age because it may cause permanent tooth discoloration and other problems. Tooth discoloration has also occurred in older children and young adults. Consult your doctor for more information.

This medication is not recommended for use during pregnancy because of possible harm to an unborn baby. Women of child-bearing age should use effective birth control while taking this medication. Consult your doctor for more details.This medication passes into breast milk in very small amounts. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.


See also How to Use.Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur: acitretin, isotretinoin, tretinoin taken by mouth.If you are currently using any of these medications, tell your doctor or pharmacist before starting minocycline.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: digoxin, live bacterial vaccines, penicillins, warfarin.

Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.

This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.


If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222.

NOTES: Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.


If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light, moisture, and excessive heat. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Taking outdated tetracycline-related drugs can result in serious illness. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.


Information specific to: Minocycline 100mg tablets when used in Acne.

minocycline acneMinocycline hydrochloride is a medicine which is used in treating acne and certain types of bacterial infections.The information in this Medicine Guide for minocycline hydrochloride varies according to the condition being treated and the particular preparation used.

Your medicine

Minocycline hydrochloride is used to treat certain types of bacterial infections including acne. It works by killing certain types of bacteria.

In treating acne, Minocycline hydrochloride works by inhibiting the growth of certain type of bacteria that may cause acne.

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Minocycline hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

*are allergic or sensitive to or have had a bad reaction to tetracyclines or medicines similar to Minocycline hydrochloride
*are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
*are breast-feeding
*are pregnant
*have asthma
*have kidney problems
*have liver problems
*have lupus or a lupus-like problem
*have myasthenia gravis

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child under the age of 12 years.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

*to check that this medicine is having the desired effect
*to check that this medicine is not having any undesired effects

Over time it is possible that Minocycline hydrochloride can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Minocycline hydrochloride has become unsuitable, it is important that the prescriber is contacted immediately.


Alcohol can interact with certain medicines.

In the case of Minocycline hydrochloride:

*this medicine may interact with alcohol

If you choose to drink alcohol while taking this medicine, it is best that you only drink alcohol in moderation. For more advice speak to your prescriber.


Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Minocycline hydrochloride:

*there are no specific foods that you must exclude from your diet when taking Minocycline hydrochloride

Driving and operating machinery

minocycline side effectsWhen taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Minocycline hydrochloride:

*this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Minocycline hydrochloride:

*this medicine may harm your baby if taken during pregnancy. If you become pregnant, or think you have become pregnant while taking Minocycline hydrochloride, you must contact your prescriber
*this medicine may make oral contraceptive pills less effective. Seek medical advice if you are taking an oral contraceptive and bleed in between menstrual periods or have diarrhoea
*you should only take this medicine during pregnancy if your doctor thinks that you need it

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Minocycline hydrochloride, then you should discuss whether there is an alternative medicine that you could take during pregnancy.


Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Minocycline hydrochloride:

*women who are breast-feeding must not take this medicine

Before you take Minocycline hydrochloride you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

Taking other medicines

minocycline acneIf you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Minocycline hydrochloride:


The following types of medicine may interact with Minocycline hydrochloride:

*ACE inhibitors
*medicines that are damaging to the liver
*medicines that are used to treat ulcers
*oral contraceptives
*preparations that contain iron, calcium, aluminium, magnesium, bismuth or zinc salts

If you are taking Minocycline hydrochloride and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins.

Make sure you tell your prescriber the names of all the complementary preparations and vitamins that you are taking or are planning to take.

Your prescriber can then decide whether it is appropriate for you to take combinations that are known to interact.

In the case of Minocycline hydrochloride:

*this medicine may interact with preparations containing minerals such as calcium, zinc, aluminium, magnesium or iron. These preparations can affect the absorption of Minocycline hydrochloride and stop it from working as well as normal

If you have been prescribed Minocycline hydrochloride you should only take something on the above list on the specific advice of your prescriber or pharmacist.


A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine’s effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

minocycline side effectsEveryone’s reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who take Minocycline hydrochloride

*feeling dizzy
*feeling light-headed

Uncommon: More than 1 in 1000 people who take Minocycline hydrochloride


Rare: More than 1 in 10,000 people who take Minocycline hydrochloride

*abnormal laboratory test results
*anaphylaxis or anaphylactic reactions including shock – these reactions could be fatal
*blood and bone marrow problems
*breathing problems – seek immediate medical advice if you have breathing difficulties, bronchospasm, an asthma attack or if your asthma becomes worse
*erythema multiforme
*hair loss
*headaches – seek medical advice if you get a headache
*hearing problems
*heart problems
*inflammation of the mouth – seek medical advice if your mouth is inflamed
*intracranial hypertension – this may lead to loss of vision. Seek medical advice if you develop blurred vision, double vision or other eye or eyesight problems
*itching – seek medical advice if you get itching around the anus
*kidney problems
*liver problems – some of these liver problems could be fatal. Seek medical advice if you develop jaundice
*loss of appetite
*lupus or lupus-like syndrome – this syndrome could be fatal. Seek medical advice if you develop symptoms such as: jointpain, swelling or stiffness, arthritis, fever, musclepain or tenderness, vasculitis, rashes or liver problems
*musclepain or tenderness
*photosensitivity skin reaction – seek medical advice if you have any skin irritation or discomfort. You should avoid exposure to direct sunlight or artificial ultraviolet light
*skin colour changes – some of these colour changes may be permanent. Seek medical advice if your skin changes colour
*skin problems
*skin rash or rashes
*teeth colour changes – some of these colour changes may be permanent. Seek medical advice if you notice any change in the colour of your teeth

Very rare: Fewer than 1 in 10,000 people who take Minocycline hydrochloride

*bulging of the fontanelle
*certain types of dermatitis
*discolouration of secretions such as sweat, tears or breast milk – some of these colour changes may be permanent. Seek medical advice if your secretions are discoloured
*infection of the anus or genitals
*infection or inflammation of the vagina and vulva – seek medical advice if you have inflammation in the vagina
*inflammation of the penis
*inflammation of the tongue – seek medical advice if your tongue is inflamed
*joint swelling or stiffness
*lung problems
*mouth infections
*nail colour changes – some of these colour changes may be permanent. Seek medical advice if you notice a change in the colour of your nails
*pseudomembranous colitis
*Stevens-Johnson syndrome
*swallowing difficulties
*thyroid problems
*tooth problems
*toxic epidermal necrolysis
*ulceration of the oesophagus
*worsening of asthma
*worsening of lupus or lupus-like problems – seek medical advice if your symptoms worsen

The frequency of these side-effects is unknown

*eye colour changes – some of these colour changes may be permanent. Seek medical advice if you notice changes to your eye colour
*hypersensitivity reactions such as unexplained or easy bruising of the skin or mucous membranes
*hypersensitivity syndrome with symptoms such as fever, lymphadenopathy, rashes or certain types of dermatitis. This syndrome may affect the heart, lungs, liver, kidneys, skin or blood and could be fatal
*may affect the results for certain tests
*overgrowth of micro-organisms that are not affected by Minocycline hydrochloride
*serum sickness-like syndrome with symptoms such as fever, urticaria, rashes, jointpain, swelling or stiffness, arthritis or blood problems. This syndrome could be fatal


Treating Acne with Oral Minocycline:

Minocycline is an oral antibiotic that is commonly prescribed for acne. It belongs to a group of antibiotics called tetracyclines (doxycycline and tetracycline also belong to this group and are also used to treat acne).Of the all the tetracyclines, minocycline is the most expensive option. But it can be effective against acne when other oral antibiotics have failed.

Minocycline has been used for decades and is especially effective against inflammatory acne, although it’s rarely used as a solo treatment. Its nearly always prescribed along with a topical acne medication. This will give you much better results than just using minocycline alone.

Also Known As:

Minocin, Dynacin, Vectrin, Solodyn (extended-release minocycline)

How It Works:

minocycline acneMinocycline works to treat acne in two ways. First, it stops the growth of bacteria that cause acne breakouts. Second, minocycline reduces inflammation. If you have red, inflamed pimples this is good news.

On the other hand, minocycline won’t do much for blackheads and other non-inflamed blemishes. A better choice in this case would be topical retinoids.

Other Oral Antibiotics Used to Treat Acne:


Common Usage Directions:

Fifty to 100 mg, one or two times a day, is a common starting dosage.

Although it’s recommended to be taken on an empty stomach, minocycline can also be taken with food. Unlike some other oral antibiotics, minocycline is absorbed really well, even with food. Not having to take it on an empty stomach is a big plus, especially for teenage boys who always seem to be hungry!

You’ll slowly taper off minocycline treatment once acne is under control. At this point, acne can often be kept in check by topical treatments alone. Sometimes, though, oral antibiotics have to be taken long-term to keep acne from returning.

Possible Side Effects:

Side effects can happen, although for most people they aren’t too uncomfortable. Just make sure to check in with your doctor if you notice any. Some of the more common side effects:

*nausea and vomiting

A bluish discoloration of the gums and mouth can also happen with minocycline use. This sounds strange and a bit scary, yes, but it generally occurs only with long term use and it is reversible. Tooth discoloration (again, of bluish nature) can happen too. It’s extremely unusual, but this one can be permanent.

Very rarely, taking minocycline can cause drug-induced lupus. Again, this is very rare and it usually goes away after stopping treatment.

Minocycline Is Not Right For:

Minocycline shouldn’t be used if you’re pregnant or breastfeeding, so let your doctor know if either of these apply to you.

Also, kids under 8 years old shouldn’t use minocycline, although some sources recommend waiting until after age 10 or even age 12. Talk to your doc to find out what’s right in your case (or your child’s).

Tips for Using Minocycline:

*Try to take your medication at about the same times every day. It helps it work better when there is a constant amount in your bloodstream.
*Take the entire course, even if your skin is looking better.
*Don’t lie down immediately after taking minocycline. Otherwise it can irritate the esophagus, which is really painful.
*Give it time. It won’t happen instantaneously, but gradually you’ll notice less redness and less breakouts altogether.


I hope this informations helped you to decide if yes or not you should use minocycline as your acne treatment.

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