Tazarotene acne treatment


Tazarotene acne treatment

Tazarotene, a topical medication for acne treatment, is effective and quite well tolerated. As Adalapene, it can be used in conjuction with other medication to increase its effectiveness. To know how to use it the right way, as well as if it causes side effects, here are the best articles from the net about tazarotene for acne.

Tazarotene Short Contact Therapy in Acne

Tazarotene belongs to the third generation of retinoids and is available in cream and gel formulations in strengths of 0.05% and 0.1% to treat acne.

Tazarotene has effects similar to other topical retinoids like tretinoin and adapalene. It normalizes the cellular differentiation in the epidermal cells and reduces their multiplication and helps limit the inflammation. It is also thought to help reduce the sebum production in acne.

Are There Any Advantages of Using Tazarotene in Acne?

Tazarotene for acneTazarotene is known as a prodrug as it metabolizes rapidly to its active metabolite, the tazarotenic acid within a matter of two to five minutes. Hence a short contact therapy of two to five minutes of higher strength (0.1%) is sufficient to produce satisfactory results, while reducing the irritant potential of the acne medication.

The medication penetrates through the spaces between the epidermal cells or through the hair follicle opening to the sebaceous glands and dermal layers to produce the anti-acne effects within this short period of time.

How is Tazarotene Applied in Acne?

A small quantity of 0.1% tazarotene gel is applied to the face where acne bumps are present and kept for 0.5 to 5 minutes and then washed off, depending upon the skin sensitivity of the patient. To start with, a two-minute application is carried out twice daily, gradually increasing or reducing the time of contact. This is known as the tazarotene short contact therapy in acne.

Tazarotene Combination Therapy in Acne

In moderate to severe types of acne combination therapy of tazarotene with benzoyl peroxide, erythromycin or clindamycin has been found to be more effective and less irritant than tazarotene used alone. Of these combinations, tazarotene short contact therapy plus benzoyl peroxide produced better results than others in terms of effectiveness and patient acceptance.

What are the Precautions to be taken While Using Tazarotene to Treat Acne?

Like other systemic and topical retinoids, tazarotene can cause severe fetal deformities if used during pregnancy. Hence, women of child bearing age group should take steps to avoid getting pregnant while on tazarotene.

What are the Other Uses of Tazarotene in Dermatology?

Tazarotene is a very useful topical agent in treating psoriasis and sun-damaged skin. Other skin diseases where tazarotene has been found effective are:

steroid induced skin damage
nail psoriasis and other forms of localized psoriasis
elastosis perforans serpiginosa
Darier’s disease
confluent and reticulate papillomatosis
basal cell carcinoma
keratoderma blenorrhagicum
juvenile acanthosis nigricans
localized discoid lupus erythematosus.

What are the Side Effects of Tazarotene in Acne?

Tazarotene irritates the skin more than other topical retinoids. It has been documented that around one third of patients who is on tazarotene experience dryness, redness, irritation, itching, stinging or excessive scaling on the face.

The short contact therapy is very effective in limiting these adverse effects of tazarotene. In individuals with very sensitive skin, the tazarotene 0.05% cream is used only to the acne lesions for two to five minutes.

Tazarotene, the new generation retinoid, is thus a very useful and safe topical acne medication useful in treatment of all types of acne, either alone or in combination with topical or oral acne medicines.


Tazarotene for acne Review

Tazarotene is a derivative of vitamin A that is prescribed as a topical gel to treat acne. The concentration of tazarotene for acne is usually 0.1% or 0.5% in gels or creams such as ‘Tazorac’. It is said to help prevent clogging of pores and therefore aid in the treatment of inflammatory acne. Another acne product that contains tazarotene is ‘Avage’. There could be other brand names for this medication too.

Topical retinoids such as tazarotene are used in the treatment of mild to moderately severe acne. They help in preventing blackheads and whiteheads.

How should Tazarotene it be used?

Tazarotene for acneTazarotene for acne is meant only for external use. This topical gel, cream or liquid is usually applied at night and you must wash affected areas 20-30 minutes before application.

Apply a thin layer to cover acne lesions alone. It must not be applied on unaffected areas. Wash your hands immediately after use. If you forget a dose and it is time to apply the next one, do so and skip the first. Do not use two doses at once. The affected areas need not be bandaged unless the doctor recommends it. Your doctor will also tell you how much and how the medicine is to be used.

Benefits of Tazarotene

Tazarotene is a synthetic retinoid that is prescribed when other medications have failed to clear acne. It is very effective in treating mild to severe acne, blackheads and whiteheads. It can also help treat acne by influencing skin cell growth.

Tazarotene works well when combined with topical antibiotics to reduce severity and frequency of acne outbreaks. It helps to unclog pores and this provides easy access to topical antibiotics that can enter the hair follicles and fight the P.acnes bacteria, which causes inflammation and infection. Oral antibiotics or benzoyl peroxide can also be used with tazarotene.

Limitations of Tazarotene

Tazarotene is meant only for certain types of acne. It produces a few side effects that must be carefully monitored. There are also certain precautions, which must be followed for the safe use of topical retinoids. This medication cannot be used unless prescribed by the doctor. Do not share it with anyone else. Acne symptoms can take time to show an improvement (at least 4 weeks). Sometimes the symptoms could get worse before they improve.

Possible Side effects

Some minor side effects of tazarotene for acne are:

*Burning or stinging sensation
*Skin irritation
*Dry skin
*Skin inflammation

If patients develop an allergic reaction to tazarotene, they can demonstrate the following symptoms:

*Severe rashes
*Difficulty in breathing
*Swelling of the face, lips, mouth or tongue
*Very severe itching, burning and redness
*Swelling of feet or hands

These symptoms rarely occur when using tazarotene. However, you must go to the nearest hospital if you develop these and other severe reactions.

Precautions with Tazarotene

Tazarotene for acne must not be used if you are allergic to tazarotene or by pregnant women. Women who use tazarotene products acne treatment must ensure they use effective birth control to avoid getting pregnant for topical retinoids can harm the unborn fetus. Patients may need to get tested for pregnancy or allowed to start tazarotene immediately after a menstrual period as a further safety measure. Breastfeeding women must inform their doctor who will decide on safety issues. Tazarotene can cause sensitivity to the sun, cold or windy weather. Protect yourself during such climates and use an adequate sunscreen when going out. You must also avoid tanning beds and sun lamps when using tazarotene to treat acne.

Drug interaction

Inform your doctor about all medications such as vitamin A supplements, antibiotics, diuretics, sulfa drugs etc., you are using. These also include OTC medications, vitamins and supplements or herbal products. Other topical acne medications or cosmetics must not be used on areas treated by tazarotene for acne. Products, which cause skin irritation or dryness such as hair removal products, exfoliating products, medicated shampoos or soaps or perm solutions, must be avoided.


Tazarotene must be stored at room temperature away from heat and light and in its original packing. It must be kept away from children or pets. It must not be poured down the drain or flushed out unless the label gives these specific disposal instructions. Properly discard the product once you have finished with it or beyond expiry date.


Although tazarotene for acne is not recommended for pregnant women, if precautions are followed, it is a very effective treatment of acne. By unclogging pores, it helps other medications like antibiotics to enter the open pores and kill the infection. While 10-30% of patients do develop mild side effects, these disappear quickly. Improvement can be seen within a few weeks


Tazorac (Tazarotene)

Tazorac Basics:

Tazarotene for acneTazorac, otherwise known as tazarotene, is a topical retinoid used to treat mild to moderate acne. It is also used to treat psoriasis.

Tazorac can be used by both teens and adults. It’s good for whiteheads and blackheads, as well as inflamed papules and pimples. This medication comes in cream and gel forms.

You will need a prescription from your doctor, though. There is no over-the-counter alternative.

Other Names for Tazorac : Tazarotene

How Tazarotene Works:

Similar to other retinoids, Tazorac works by speeding up cell turnover rates and keeping pores free from blockages. Because skin cells aren’t hanging around in the pore as long, comedones and other blemishes are reduced.

Common Usage Directions:

Your doctor will probably instruct you to use this medication once daily. Gently rub Tazorac into the skin over all acne-prone areas.

Just a pea-sized amount is enough for the whole face. Although this seems like a tiny amount of medication, using more isn’t necessary.

Results are usually seen within four to 12 weeks.

Possible Side Effects:

You knew there had to be some. But don’t worry, the possible side effects of Tazorac are similar to other topical retinoids. When using Tazorac, you may notice:

Burning or stinging
Increased sensitivity to the sun (photosensitivity)
General skin irritation

Although more serious side effects aren’t as common, be on the lookout for:

Skin rash and/or hives
Cracking or bleeding skin
Skin discoloration

Most importantly, don’t use Tazorac if you’re pregnant. Tazorac is a FDA Pregnancy Category X drug, which means it can cause birth defects if used during pregnancy.

Birth control must be used while you’re taking Tazorac. Ladies, your doctor may have you take a pregnancy test two weeks before starting Tazorac and/or will have you start using the medication during your period.

Tazorac also passes to breast milk, although we don’t know how it affects a nursing infant. Obviously, you’ll want to discuss this with your doctor if you are breastfeeding.


If home remedies didn’t work for you, you can try retinoids. I hope the articles above gave you enough informations about Tazarotene for acne and will help you treat your skin.

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